- Transfer printing of inorganic semiconductors is a key technology to realize next-generation human augmented optoelectronics. Prof. Lee’s group has developed a novel micro-vacuum assisted selective transfer (μVAST) process to integrate inorganic thin-film semiconductor arrays on unconventional substrates for high-performance flexible optoelectronics.
- Light is a powerful medium to increase cognitive and physical abilities of human bodies by expanding human vision and tissue functionalities. Prof. Lee’s group has developed 2D/3D microfabrication and microLEDs transfer technology to implement see-through/head-up microLED displays, light-induced neural modulators and therapeutic light stimulators.
- Achieving effective light delivery to solid tumors with dynamic volumetric changes, such as pancreatic cancer, is a crucial requirement for successful photodynamic therapy. In this regard, Prof. Lee’s group has developed a deeply implantable, wirelessly operated, and shape-morphing 3D micro-LED (SMLED) that conformally adheres to the 3D curved surface of orthotopic pancreatic tumors, enabling continuous and targeted metronomic photodynamic therapy (mPDT) to alleviate desmoplasia and induce tumor cell death without delamination.
- Conformal attachment of electronic devices on the brain surface and wireless power delivery are key technologies to realize next-generation AI-brain interfaces. Our group has developed high-performance flexible vertical inorganic light-emitting diodes (f-VLEDs) using anisotropic conductive films to integrate flexible biomedical optoelectronics for simultaneous biomedical disease sensing and neural optogenetic control.
[Related References]
"Bio-Integrated Flexible Inorganic LED", Nanobiosensors in Disease Diagnosis, 1, 5, 2012
"Water-resistant Flexible GaN LED on a Liquid Crystal Polymer Substrate for Implantable Biomedical Applications", Nano Energy, 1, 145, 2012
"Optogenetic Control of Body Movements via Flexible Vertical Light-Emitting Diodes on Brain Surface", Nano Energy, 44, 447, 2018
"Monolithic Flexible Vertical GaN Light-Emitting Diodes for Transparent Wireless Brain Optical Stimulator", Adv. Mater. 30, 1800649, 2018
"Trichogenic Photostimulation Using Monolithic Flexible Vertical AlGaInP Light-Emitting Diodes", ACS Nano, 12, 9587, 2018
"Progress in Brain-Compatible Interfaces with Soft Nanomaterials ", Advanced Materials, 32, 1907522, 2020
“Wearable Surface-Lighting Micro-Light-Emitting Diode Patch for Melanogenesis Inhibition.”, Adv. Healthcare Mater., 12, 2201796. 2023
"Clinical Validation of Face-fit Surface-lighting micro LED Mask for Skin Anti-aging Treatment" Adv. Mater. 36, 2411651, 2024
"Deeply Implantable, Shape-Morphing, 3D MicroLEDs for Pancreatic Cancer Therapy", Adv. Mater. 37, 2411494, 2025
